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目的:考察化痔片的抗炎镇痛及抗直肠溃疡作用。方法:采用二甲苯涂耳致小鼠耳肿胀法,新鲜蛋清致大鼠后足踝关节肿胀法,醋酸致小鼠扭体法,小鼠热板致痛舔后足法,金黄色葡萄球菌合并外力损伤致家兔直肠溃疡法,考察化痔片的作用。结果:化痔片对二甲苯致小鼠的耳肿胀和新鲜蛋清致大鼠的足肿胀急性炎症有显著的抑制作用;对醋酸致小鼠扭体及热板致小鼠后足烫痛均有显著的镇痛作用;对金黄色葡萄球菌合并外力损伤致家兔直肠的溃疡有明显改善作用。结论:化痔片具有良好的抗炎、镇痛及抗直肠溃疡作用。
Objective: To investigate the anti-inflammatory analgesic and anti-rectal ulcer effects of Huatan tablets. METHODS: Xylene ear-induced mouse ear swelling method, fresh egg white-induced rat hind paw articular swelling method, acetic acid-induced mouse writhing method, mouse hot plate induced dysentery posterior foot method, Staphylococcus aureus merger External damage caused by rectal ulcer method in rabbits, to investigate the role of phlegm tablets. RESULTS: Huatan Tablets had significant inhibitory effects on the ear swelling of mice induced by xylene and the acute inflammation of foot swelling induced by fresh egg whites; Significant analgesic effect; significant improvement of Staphylococcus aureus combined with external damage caused by rectal ulcers in rabbits. Conclusion: Huatan tablets have good anti-inflammatory, analgesic and anti-rectal ulcer effects.