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目的 观察医用聚丙烯酰胺水凝胶对周围神经的影响。方法 聚丙烯酰胺水凝胶稀释后 ,以 16号针头注射到兔坐骨神经外膜内及其周围。注射量为 0 .5～ 1.0ml,观察兔趾展反射、神经动作电位及电传导速度。结果 聚丙烯酰胺水凝胶周围形成透亮薄层包膜。兔双侧趾展反射正常 ,双侧坐骨神经肉眼观察色泽、粗细均无差别 ,神经电生理检查动作电位及电传导速度也基本相同。结论 聚丙烯酰胺对兔坐骨神经无明显不利影响
Objective To observe the effect of medical polyacrylamide hydrogel on peripheral nerve. Methods After diluted with polyacrylamide hydrogel, a 16-gauge needle was injected into and around the sciatic nerve adventitia. Injection volume of 0.5 ~ 1.0ml, observe rabbit toe reflex, nerve action potential and electrical conduction velocity. Results A polyacrylamide hydrogel was formed around the translucent lamellar envelope. Rabbit bilateral normal toe reflex, bilateral visualization of the sciatic nerve color, thickness were no difference, the nerve electrophysiological examination of action potential and electrical conduction velocity are basically the same. Conclusion Polyacrylamide has no adverse effect on sciatic nerve in rabbits