口服避孕药(OCs)自从1960年面世以来,由于其避孕效果可靠,停药后不影响再孕,逐渐成为世界上应用最广泛的避孕方法之一。四十多年来国内外的研究者们不断地研制出更加安全、可靠、有效的OCs。OCs的主要组成成分孕激素在化学组成上更是经历了许多的发展变化。现就孕激素在OCs中的应用及其新的进展做一简要综述。 Oral contraceptives (OCs) Since its introduction in 1960, it has become one of the most widely used contraceptive methods in the world due to its reliable contraceptive effect and its effect on pregnancy after stopping its administration. For more than 40 years, researchers at home and abroad have been continuously developing more secure, reliable and effective OCs. The main component of OCs progesterone in the chemical composition is undergoing many changes. Now on the application of progesterone in OCs and its new progress to make a brief review.