Background Degloving injuries are severe and frequently underestimated lesions.Lower extremities are the most commonly affected limbs.This injury is associated with a high morbidity and mortality if mismanaged.The treatment of such patients still varies and clinical indicators for its prognosis are scarce,and some technical protocols are also controversial.Purpose The purpose of this study is to present our detailed techniques in management of degloving injuries of lower extremities and summarize the outcomes of different patterns and age groups in this series in an attempt to provide a better means of assessing this injury in the lower extremity.Methods Between August 2002 and July 2011,102 patients with circumferential skin avulsion of 129 lower extremities were treated with immediate full-thickness skin graft following a protocol of radical debridement.The full—thickness skin grafts were processed with sharp scalpels in situ.They were further secured with multiple sutures after repositioning to improve skin graft take.Outcomes were evaluated based on different patterns and age groups.Results The preparation of full-thickness skin graft with scalpels is a simple and prompt procedure.Three patterns of injury,that is,purely degloving injury,degloving injury with the involvement of deep soft tissues and degloving injury with the involvement of long bone fractures were revealed.Among the three patterns,much higher primary healing rates were observed in pattern 1 and 2;younger patients in pattern 3 achieved a higher primary healing rate than the old ones,while no differences of primary healing rate regarding different age groups were noted in pattern 1 and 2.Conclusions Satisfactory outcomes were achieved with immediate full-thickness skin grafting following the protocol of radical debridement in all cases apart from some cases in pattern 3 who may need staged reconstruction.In pattern 3,old age is an indicator of unfavourable outcome and special attention is required.