How Supramolecular Chemistry interplays between the Eastem Philosophy and the Complexity Theory relationship? Taking suggestion from the old eastem philosophy and observing the recent westem theory in this paper we will evidence some analogies between the two apparent different thoughts and show that both approaches want to know more about the emerging of life from inanimate matter. In this perspective we underline that Supramolecular Chemistry, investigating the emerging behaviour or properties of the whole complex system. has a central role to understand the spontaneous evolution of Nature. We report on a few aspects of supramolecular chemistry of guanosine derivatives and their implications in material sciences, medicine and nanotechnology.　　 The chirality is one of the most important geometrical properties in the organic and biological world. The natural processes: auto-recognition and self-assembling, are both the driving forces of all the living systems either at molecular leVel or at cellular level. The applications of new chiral nanomaterial are powerful tools in all the scientific fields where the molecular recognitions is the fundamental process under study (sensor, bioimaging, biointerface recognition process, drug deliver, cancer therapy, asymmetric catalysis and enantioselective separation). For this purpose we used the molecule guanosine 5-monophosphate (5-GMP) as organic chiral ligand to impose a chiral environment for the preparation of an optical active Iigand protected gold nanostructures. Different reducing agents have been used to obtain new chiral metal nanostructure morphologies.　　 We report the chemical reduction of silver ions incorporated into chiral supramolecular nanostructures by NaBH4 in buffered (basic) and unbuffered conditions. In situ self-assembly of guanosine 5-monophosphate (5-GMP) templated by Ag(Ⅰ) and generation of silver nanoparticles (NP) were continuously monitored by CD and UV-Vis spectroscopy measurements. 5-GMP has been identified as an efficient chiral organic ligand to complex silver ions into a hierarchical helical nanostructure and is a useful capping agent for stabilizing silver NPs with a size diameter lower than 20 nm. The observation of opposite signed bands in the CD spectra of Ag(Ⅰ)/5-GMP complexes at different pH has suggested the existence of opposite- handed supramolecular helical structures depending on pH. Both helical supramolecular structures induce chirality in the silver NPs during their growth of the same handedness as shown by the CD signals in plasmon resonance band.　　 The effective contribution that Microreactor Technology (MRT) could bring in the process of nanomaterials production is widely discussed. Among many possible applications for microfluidic devices it is a challenge to generate a concentration gradient, i.e to perform analytical serial dilution for μTAS or to carry out chemical reaction with different molar ratio of reagents, this is one of the main task to develop a Iab-on-chip platform.　　 Many approaches have been developed to create aqueous gradient solutions, but the complexity of such systems have limited their use. We present a PDMS/glass-based microfluidic device based on a new and compact geometry for the generation of sigmoidal concentration gradient. The optimal geometry design of the micromixer system has been improved by Comsol simulation implementing fluid flow and chemical transport analysis. The production of the prototype and the experiment results are compared with the simulation data to verify its performance.