This study has been conducted to isolate epidermal stem cells from Cashmere goat fetus and to characterize them in stem cell nature. Here we also report the isolation of a stem cell population from dermis (also termed as skin derived precursor cells) having multilineage differentiation capacity. This study was categorized into four parts to accomplish the research objectives. Part A: Keratinocyte isolation and euRure from goat fetus skin Part B: Putative epidermal stem cell selection. propagation and characterization Part C: Identification of epidermal stem cells by molecular marker expression Part D: Directional differentiation of skin stem cells