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目的探讨护理干预联合中医治疗小儿神经母细胞瘤(NB)化疗后疲乏的临床疗效。方法选取2015年1月至2016年1月间德州市陵城区人民医院收治的68例NB患者,采用随机数表法分为观察组和对照组,每组34例。两组患者均服用来复汤中药治疗,观察组患者给予循证护理干预,对照组患者给予常规护理。分别于治疗前后采用Piper疲乏量表和生活质量评分量表评价治疗效果。结果两组患者治疗后疲乏程度均较治疗前有所缓解,差异均有统计学意义(均P<0.05),治疗后观察组患者疲乏程度低于对照组患者,差异有统计学意义(P<0.05)。治疗后两组患者躯体功能、角色功能、认知功能、情感功能、社会功能和总体健康评分均显著提高,差异均有统计学意义(均P<0.05),观察组患者功能量表各项评分和总体健康评分显著高于对照组患者,差异均有统计学意义(均P<0.05)。治疗后两组患者生活质量症状量表各项评分均显著降低,差异均有统计学意义(均P<0.05),观察组患者生活质量症状量表各项评分显著低于对照组患者,差异均有统计学意义(均P<0.05)。结论护理干预联合中医治疗可以有效的缓解小儿NB化疗后的疲乏,提高生活质量,有较好的疗效。
Objective To investigate the clinical effects of nursing intervention combined with traditional Chinese medicine on the treatment of pediatric neuroblastoma (NB) chemotherapy after fatigue. Methods Sixty-eight patients with NB who were treated in Lingcheng District People’s Hospital of Dezhou from January 2015 to January 2016 were randomly divided into observation group and control group with 34 cases in each group. Two groups of patients took Fufang Tang Chinese medicine treatment, observation group patients were given evidence-based nursing intervention, patients in the control group were given routine care. Before and after treatment, Piper fatigue scale and quality of life scale were used to evaluate the therapeutic effect. Results After treatment, the degree of fatigue in both groups was relieved before treatment, with significant difference (all P <0.05). After treatment, the degree of fatigue in the observation group was lower than that in the control group (P < 0.05). After treatment, the body function, role function, cognitive function, emotional function, social function and overall health score were significantly increased in both groups (all P <0.05). The scores of functional scale in the observation group And the overall health score was significantly higher than that of the control group, the differences were statistically significant (P <0.05). After treatment, the scores of quality of life in both groups were significantly reduced, the differences were statistically significant (P <0.05), the quality of life of patients in the observation group was significantly lower than the scores of the control group, the difference was There was statistical significance (all P <0.05). Conclusion Nursing intervention combined with traditional Chinese medicine treatment can effectively alleviate the fatigue after pediatric NB chemotherapy, improve the quality of life, have a good effect.