研究发现人参皂苷具有抗肿瘤效果,尤其能抑制肿瘤内血管形成并阻止肿瘤浸润及转移。人参皂苷口服很难被胃液及肝脏中的酶分解,多数在肠中吸收。人参皂苷口服后经肠道菌群的脱糖基作用,其主要代谢产物为M1,即20-O-β-D-吡喃葡糖基-20(S)-原人参二醇。M1静脉注射给予小鼠后,选择性地在肝脏中蓄积,并经胆汁排泄;另有一些M1在肝脏中转化为相应的脂肪酸酪EM1,在大鼠肝中回收量 Studies have found that ginsenosides have an anti-tumor effect, in particular, they can inhibit the formation of blood vessels in tumors and prevent tumor invasion and metastasis. Ginsenosides are difficult to be orally digested by gastric juices and enzymes in the liver and are mostly absorbed in the intestine. After oral administration of ginsenosides, the main metabolite of the ginsenosides is M1, 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol. M1 was intravenously administered to mice, selectively accumulated in the liver, and excreted in the bile; another M1 was converted into the corresponding fatty acid yolk EM1 in the liver and recovered in the rat liver.