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目的 比较国产与进口氟康唑注射剂治疗深部真菌病临床疗效与安全性。方法 在 170例深部真菌病患者中作了前瞻性多中心研究。结果 试验组 (T组 )与对照组 (C组 )临床综合疗效痊愈率 (5 0 .9%和 5 0 .9% )、有效率 (83.6 %和89.1% )、致病菌株清除率 (83.9%和 89.1% )和不良反应发生率 (8.9%和 9.1% )之间差异均无显著性 (P>0 .0 5 )。结论 国产与进口氟康唑注射液都是安全、有效的抗真菌药物。
Objective To compare the clinical efficacy and safety of domestic and imported fluconazole in the treatment of deep mycosis. Methods A prospective, multicenter study of 170 patients with deep mycosis was performed. Results The cure rate (83.6% and 89.1%), the pathogenic strain clearance rate (83.9%) in the trial group (T group) and the control group (C group) % And 89.1%) and the incidence of adverse reactions (8.9% and 9.1%), respectively. There was no significant difference (P> 0.05). Conclusion Both domestic and imported fluconazole injection are safe and effective antifungal drugs.