目的评价B超引导下经皮肾镜碎石取石术治疗复杂性肾结石的疗效及安全性。方法收集并分析2005～2012年586例完成该手术的复杂性肾结石患者资料。结果手术均取得成功,一期结石取净率86.7%,术后平均住院时间8 d。6例术中出血较多行二期手术;3例术后出血行高选择性肾动脉栓塞,2例术后出现肾周感染行穿刺引流。结论 B超引导下经皮肾镜碎石取石术治疗复杂性肾结石安全、有效,尤其对开放手术难度大的患者优势明显。 Objective To evaluate the efficacy and safety of B-guided percutaneous nephrolithotomy in the treatment of complex renal calculus. Methods The data of 586 patients with complicated renal calculi who completed the operation from 2005 to 2012 were collected and analyzed. Results All the operations were successful. The first-stage stone removal rate was 86.7% and the average postoperative hospital stay was 8 days. In 6 cases, hemorrhage occurred more often in the second stage of operation. In 3 cases postoperative hemorrhage, high selective renal artery embolization was performed. In 2 cases, peripheral peritonitis was punctured and punctured. Conclusion B-guided percutaneous nephrolithotomy lithotripsy for the treatment of complex renal stones safe and effective, especially for patients with open surgery difficult to obvious advantages.