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类风湿性关节炎(RA)是一种慢性炎症性疾病,其重要特征是关节滑膜增生,并形成血管翳,从而导致骨质的破坏。有效阻断滑膜增生和血管翳的形成有助于病情改善,故而加紧对中医药阻止关节炎症和阻断骨质破坏的机制研究具有重要意义。本文观察了化痰祛瘀法对AA大鼠凝血纤溶系统的影响,并对相应机制进行探讨。1实验材料1.1实验动物大鼠共72只,雄性,清洁级,由中国科学院上海实验动物中心提供,上海中医药大学附属龙华医院动物饲养中心SPF级饲养。1.2实验药物化痰祛瘀小复方(莪术30g、三七6g、制南
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovial hyperplasia of the joints and the formation of blood vessels that lead to the destruction of bone. Effective blocking of synovial hyperplasia and angiogenesis help to improve the condition, so it is of great significance to study the mechanism of traditional Chinese medicine in preventing joint inflammation and blocking bone destruction. This article observed the phlegm and blood stasis on the coagulation fibrinolytic system in AA rats, and to explore the corresponding mechanism. 1 Experimental Materials 1.1 Experimental animals A total of 72 rats, male, clean level, provided by the Shanghai Laboratory Animal Center, Chinese Academy of Sciences, Shanghai Traditional Chinese Medicine University Longhua Hospital Animal Feed Center SPF feeding. 1.2 Experimental drug phlegm stasis small compound (Curcuma 30g, 376g, South