正常人体由于肾小球的有限滤过以及肾小管重吸收功能,尿液中的白蛋白(albumin,Alb)含量极为有限。但当免疫或非免疫因素损害肾小球滤过屏障或者肾小管功能发生障碍时,尿中Alb排泄量会显著增加。研究发现,肾小管间质病变进展速度与尿蛋白含量有关,降低尿蛋白可延缓肾脏疾病进展[ Normal human urine albumin (albumin, Alb) content is extremely limited due to the limited filtration of glomerular and tubular reabsorption. However, when immune or non-immune factors impair the glomerular filtration barrier or renal tubular dysfunction occurs, the urinary Alb excretion will be significantly increased. The study found that the progress of tubulointerstitial lesions and urinary protein content, reduce proteinuria can delay the progress of kidney disease [