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雪上一枝蒿为剧毒药。本文对不同产地(包括家种)和不同炮制方法的雪上一支蒿总碱含量作了实验比较,其重点是将生药与五种炮制品测定的LD_(50)和镇痛作用作了比较。实验结果表明:不同产地和不同炮制方法的雪上一支蒿总碱含量均不相同。经筛选出的四个炮制品,不仅毒性大大降低,而且保持了疗效。其中尤以水煎品方法简便,质量较优。
Snow on a branch of Artemisia is highly toxic. In this paper, the total alkaloid content of Artemisia sphaerocephala in different producing areas (including domestic species) and different processing methods was compared experimentally. The main point was to compare the LD 50 and analgesic effects measured by crude drugs and five processed products. The experimental results show that the contents of total alkaloids in Artemisia sphaerocephala are different in different producing areas and different processing methods. The four processed products that have been screened not only have greatly reduced toxicity, but also maintain their efficacy. Among them, the method of water decoction is simple and the quality is superior.