本文报道129例不同孕龄正常妇女、51例病理妊娠血PRL测定及18例剖宫产时的羊水、脐血.母血配对检查结果,妊娠期PRL值自早孕开始随孕月增加而升高,妊娠足月时可达非孕妇女17倍;重度妊娠高血压综合征及妊娠合并慢性肾小球肾炎PRL值显著高于同孕龄妇女,妊娠合并糖尿病PRL值低于正常孕妇,P值均<0.01;中度妊娠高血压综合征、羊水过多则增高不明显。剖宫产妇血、羊水、脐血PRL均值分别为6873.83 mU/L、31050.89 mU/L、9675.44 mU/L,即PRL值为羊水>脐血>母血,此结果支持妊娠期除垂体外蜕膜组织也有产生大量PRL的观点。 This paper reports 129 normal pregnant women of different gestational ages, 51 cases of pathological pregnancy blood PRL determination and 18 cases of cesarean section of amniotic fluid, cord blood maternal paired test results, pregnancy PRL value increased with pregnancy from the first pregnancy increased , Pregnant women up to 17 times the full pregnancy; women with severe pregnancy-induced hypertension and pregnancy associated with chronic glomerulonephritis PRL value was significantly higher than the same gestational age women, PRL value of pregnancy with diabetes mellitus was lower than normal pregnant women, P value <0.01; moderate pregnancy induced hypertension, oligohydramnios increased is not obvious. The average PRL of cesarean section maternal blood, amniotic fluid and umbilical cord blood were 6873.83 mU / L, 31050.89 mU / L and 9675.44 mU / L respectively, which means PRL value was amniotic fluid> cord blood> maternal blood. Membrane tissue also produces a large number of PRL point of view.