卡马西平(carbamazepine,CBZ)是临床上常用的抗癫痫药物。常见的副反应有头晕、嗜睡、乏力、恶心、呕吐,偶尔引起白细胞减少,血小板减少,再生障碍性贫血、黄疸、肝功能不全、蛋白尿、充血性心力衰竭等。因此长期用药应定期检查血象、尿常规,以防蓄积中毒。欧美等国把CBZ列为必须进行血药监测的常规药物。作者采用紫外分光光度法测定CBZ的血药浓度。 Carbamazepine (CBZ) is a commonly used antiepileptic drug in clinic. Common side effects are dizziness, drowsiness, fatigue, nausea, vomiting, and occasionally cause leukopenia, thrombocytopenia, aplastic anemia, jaundice, liver dysfunction, proteinuria, congestive heart failure. Therefore, long-term medication should be checked regularly blood, urine, to prevent accumulation of poisoning. Countries such as Europe and the United States put CBZ as a routine drug for blood drug monitoring. The author uses ultraviolet spectrophotometry to determine the blood concentration of CBZ.