论文部分内容阅读
目的:探讨重症手足口病(hand food mouth disease,HFMD)的中医体质与中医证型的分布特征及实验室指标的关联性。方法:收集200例重症HFMD患儿,进行一般资料分析,评估中医体质类型、中医辨证分型,并检测常见神经系统受累及心肌损害的实验室指标。结果:重症HFMD患儿偏颇体质占85%,其中特禀质(28%)、气虚质(25%)、阳虚质(13.5%)占多数;重症HFMD中医证型主要为热扰心肝证(94%);重症HFMD患儿神经烯醇化酶(NSE)、谷草转氨酶(AST)、乳酸脱氢酶(LDH)、肌酸激酶同工酶(CK-MB)均明显升高,其中热扰心肝证患儿NSE升高明显(P<0.05),可作为该证型的微观化敏感指标。结论:特禀质、气虚质、阳虚质类体质更易发展为重症HFMD;该病主要表现为热扰心肝证,NSE可作为该证型的微观化敏感指标。
Objective: To investigate the distribution characteristics of traditional Chinese medicine (TCM) and TCM syndromes and the correlation between laboratory indexes in patients with severe hand-foot-mouth disease (HFMD). Methods: Two hundred children with severe HFMD were collected and analyzed by general data to evaluate the types of TCM, the syndrome differentiation of TCM, and the laboratory indexes of common nervous system involvement and myocardial damage. Results: The patients with severe HFMD accounted for 85% of the patients with biased constitution, of which 28% had intrinsic consotility, 25% had deficiency of qi and 13.5% 94%). The levels of neuron enolase (NSE), aspartate aminotransferase (AST), lactate dehydrogenase (LDH) and creatine kinase (CK-MB) in children with severe HFMD were significantly increased NSE children with evidence increased significantly (P <0.05), can be used as a micro-sensitive indicators of the syndrome. Conclusion: The constitution of special quality, qi deficiency and yang deficiency is more likely to develop severe HFMD. The disease mainly manifests as heat disturbance of liver and liver syndrome, and NSE can be used as the micro-sensitivity index of this syndrome.