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Toll样受体(Toll like receptors,TLRs)是近些年来发现的一类新的细胞表面信号传导跨膜受体,能够识别作为配体的病原相关的分子模式(Pathogen-as-sociated molecular patterns,PAMPs),是人体固有免疫和适应性免疫的桥梁[1]。TLRs被内、外源性配体不恰当的激活,分子模拟和抗原提
Toll-like receptors (Toll-like receptors, TLRs) is a new type of cell surface signal transduction transmembrane receptor found in recent years, which can recognize the pathogen-as-associated molecular patterns PAMPs), is a bridge between innate and adaptive immunity [1]. TLRs are inappropriately activated by endogenous and exogenous ligands, molecular mimicry and antigen retrieval