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目的观察中西医结合治疗重度慢性阻塞性肺病(COPD)稳定期的临床疗效。方法将本院2013年8月-2014年12月门诊的重度COPD患者(FEV1%<50%)72例分为治疗组和对照组,两组各36例,治疗组在对照组的基础上给予自拟中药口服,每日1剂,3月为1个疗程。两组均治疗2个疗程。结果治疗14d后,治疗组总有效率为94.4%,对照组为83.3%,两组总有效率比较差异有统计学意义(P<0.05)。两组治疗后FEV1/FVC及FEV1占预计值的百分比,组间比较差异有统计学意义(P<0.05),治疗组优于对照组。结论中西医结合治疗COPD,能明显改善临床症状,改善肺功能,且安全性好,值得临床推广应用。
Objective To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of patients with severe chronic obstructive pulmonary disease (COPD) in stable phase. Methods Seventy-two outpatients with severe COPD (FEV1% <50%) in our hospital from August 2013 to December 2014 were divided into treatment group and control group, with 36 cases in each group. The treatment group was given on the basis of the control group Since the oral administration of traditional Chinese medicine, day 1, March for a course of treatment. Two groups were treated 2 courses. Results After treatment for 14 days, the total effective rate was 94.4% in the treatment group and 83.3% in the control group. The total effective rate was significantly different between the two groups (P <0.05). The percentages of FEV1 / FVC and FEV1 in the two groups after treatment were statistically significant (P <0.05). The treatment group was better than the control group. Conclusion The combination of TCM and Western medicine treatment of COPD can significantly improve clinical symptoms and improve lung function, and the safety is good, worthy of clinical promotion and application.