临床医学试验研究中,选题、设计确定以后,采取样本大小也是一个重要的问题。当前临床医学论文中,由于采取样本不当,往往直接影响研究的结论,值得引起注意。临床上对某种疾病全部对象进行研究,称为总体,这样观察出来的结果才能真正反映疾病的客观规律。但实际临床研究中,由于种种因素,不可能对某种疾病全部都进行研究,因此只能抽样一部分病例作为研究对象,以代表总体的 In clinical trials, the size of the sample is also an important issue after the selection of topics and design. In current clinical medical papers, due to the improper sampling, it often directly affects the conclusion of the research and deserves attention. The study of all subjects of a certain disease in the clinic is called overall, so that the observed results can truly reflect the objective law of the disease. However, in actual clinical research, due to various factors, it is impossible to study all diseases. Therefore, only a part of cases can be sampled to represent the overall population.