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目的探讨新疆和田地区维吾尔族乙型肝炎病毒(HBV)感染后发生慢性乙型肝炎的影响因素。方法选取新疆和田地区维吾尔族慢性乙型肝炎患者54例、HBV携带者51例,回顾性分析HBV感染后发生慢性乙型肝炎的影响因素。结果慢性乙型肝炎患者、HBV携带者乙肝家族史、抗-HBe阳性、乙肝基因型C型(C型HBV)差异均有统计学意义(P均<0.05),年龄、性别、BMI、HBe Ag阳性、HBV DNA定量差异均无统计学意义(P均>0.05)。乙肝家族史、C型HBV为HBV感染致慢性乙型肝炎发病的独立影响因素(P均<0.05)。结论乙肝家族史、抗-HBe阳性、C型HBV是新疆和田地区维吾尔族HBV感染致慢性乙型肝炎的影响因素。
Objective To investigate the influencing factors of chronic hepatitis B after Uygur hepatitis B infection in Hetian area, Xinjiang. Methods 54 Uygur patients with chronic hepatitis B and 51 cases of HBV carriers were selected from Hetian, Xinjiang. The influencing factors of chronic hepatitis B after HBV infection were retrospectively analyzed. Results There were significant differences in the family history of hepatitis B, anti-HBe positive and hepatitis C genotype C (HBV C) among patients with chronic hepatitis B (all P <0.05), age, gender, BMI, HBeAg Positive, HBV DNA quantitative differences were not statistically significant (P all> 0.05). Family history of hepatitis B and type C HBV were the independent influencing factors of HBV infection in chronic hepatitis B (all P <0.05). Conclusion The family history of hepatitis B, anti-HBe positive and C-type HBV are the influencing factors of chronic hepatitis B in Uygur HBV infection in Hetian area.