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在HIV感染流行之初,就观察到HIV与梅毒共感染在一些特殊人群如男男性行为(MSM)中发病率显著升高,梅毒可以增加HIV感染的易感性,HIV感染使梅毒的临床表现具有非典型性,增加神经梅毒的风险等,使得梅毒的诊断治疗更加复杂和具有挑战性。文中综述了梅毒与HIV共感染的流行状况,梅毒对HIV传播的影响,HIV感染对梅毒临床表现及治疗的影响,以及在该领域的最新进展。
At the beginning of the HIV epidemic, co-infection with HIV and syphilis was observed to be significantly increased in some special populations such as men who have sex with men (MSM), syphilis increased the susceptibility to HIV infection and HIV infection provided the clinical manifestations of syphilis with Atypical sex, increasing the risk of neurosyphilis, making the diagnosis and treatment of syphilis more complex and challenging. This article reviews the prevalence of syphilis and HIV co-infections, the impact of syphilis on HIV transmission, the impact of HIV infection on the clinical presentation and treatment of syphilis, and recent advances in this area.