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目的:探讨克罗米芬、绝经后尿促性腺激素、来曲唑3种不同药物对多囊卵巢综合征(PCOS)患者促排卵效果以及血清生殖激素的影响。方法:收集接受治疗的PCOS患者120例,随机分为A、B、C组各40例。A组给予克罗米芬治疗,B组给予绝经后尿促性腺激素治疗,C组给予来曲唑治疗,比较3组促排卵效果以及血清生殖激素水平。结果:B组周期妊娠率26.67%,C组周期妊娠率31.83%,均高于A组周期妊娠率8.33%(P<0.05)。A、C组雌二醇水平均高于B组(P<0.05)。结论:临床应根据患者个体情况选取合适的药物,制定个性化方案,促进患者排卵及激素分泌,提高受孕率。
Objective: To investigate the effects of clomiphene, postmenopausal ursoderm and letrozole on ovulation induction and serum reproductive hormones in women with polycystic ovary syndrome (PCOS). Methods: A total of 120 PCOS patients were collected and randomly divided into A, B and C groups of 40 cases. Group A received clomiphene, group B received postmenopausal urogenital gonadotropin, group C received letrozole, and compared three groups of ovulation induction and serum reproductive hormone levels. Results: The pregnancy rate of group B was 26.67%, and that of group C was 31.83%, which was higher than that of group A (8.33%, P <0.05). The estradiol levels in groups A and C were higher than those in group B (P <0.05). Conclusion: According to the individual patient’s clinical selection of appropriate drugs, to develop personalized programs to promote ovulation and hormone secretion and improve pregnancy rate.