论文部分内容阅读
目的:对依达拉奉用于急性脑梗塞的临床治疗进行探讨。方法:对2008年5月至2010年4月我院收治的106例经由脑颅MRI或CT确诊的早期急性脑梗塞患者,进行随机分组,其中对照组61例,观察组45例,观察组在对照组的治疗基础上追加依达拉奉静脉注射。两组患者的年龄、性别、病程等临床资料不存在显著性差异,具有可比性。结果:观察组患者神经功能缺损的减少比对照组明显,日常生活能力也比对照组显著提高,两组差异具有显著性(P<0.05),并且随治疗的时间增加还会加大治疗效果差异。结论:依达拉奉具有抑制脂质过氧化、清除自由基的作用,能够对脑神经起到保护作用,阻止脑梗塞进一步发展,使患者伴发的神经症状缓解,患者的预后生存质量大大提升。
Objective: To investigate the clinical application of edaravone in acute cerebral infarction. Methods: From May 2008 to April 2010 in our hospital, 106 cases of early acute cerebral infarction confirmed by brain MRI or CT were randomly divided into control group (61 cases), observation group (45 cases) and observation group Control group based on additional treatment with edaravone intravenously. Two groups of patients age, gender, duration and other clinical data there is no significant difference, comparable. Results: The decrease of neurological deficit in the observation group was more obvious than that of the control group, and the daily living ability of the patients in the observation group was significantly higher than that in the control group (P <0.05). The treatment effect was also increased with the increase of the treatment time . Conclusion: Edaravone inhibits lipid peroxidation and scavenging free radicals, which can protect the cranial nerves, prevent the further development of cerebral infarction, relieve the neurological symptoms associated with patients and greatly improve the prognosis of patients with quality of life .