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为了研究性早熟患儿的生长激增是否与生长激素(GH)分泌升高有关,作者测定51例中枢性性早熟儿童(女47,男4,年龄3～9岁)24小时 GH 浓度谱,并与23名年龄匹配的正常儿童(女12,男11,年龄4～9岁)相比较。性早熟的诊断是根据第二性征过早出现、骨龄和生长激增而确定。并通过测定基础性激素水平,黄体生成素释放激素(LH-RH)兴奋试验,盆腔、肾上腺超声检查,头部 CT,血清17-羟孕酮、11-去氧皮质醇,绒毛膜促性腺激素等试验,以确定性早熟的
To investigate whether growth arrest in precocious puberty is associated with increased GH secretion, we determined the 24 h GH concentration profile in 51 children with central precocious puberty (47 women, 4 men and 3-9 years of age) and Compared with 23 age-matched normal children (12 women, 11 men and 4 to 9 years old). Diagnosis of precocious puberty is based on the second signs of premature emergence, bone age and growth surge to determine. And by measuring the basic hormone levels, LH-RH excitement test, pelvic, adrenal ultrasound examination, head CT, serum 17-hydroxyprogesterone, 11-deoxy cortisol, chorionic gonadotropin, etc. Test to determine precocious