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目的:评价干扰素-α2a栓对宫颈糜烂人乳头瘤病毒(HPV)感染患者抗病毒治疗的临床疗效。方法:选取2014年2月—2016年10月期间收治的HPV所致宫颈糜烂患者122例,将其随机分为A组和B组,每组61例;B组患者给予微波治疗,A组患者在B组治疗的基础上加用干扰素-α2a栓抗病毒治疗,评价两组患者治疗前后阴道分泌物的清洁度、总有效率和临床各症状缓解率。结果:治疗前两组患者的阴道分泌物检查结果示正常率经比较其差异无统计学意义(P>0.05);治疗后A组患者的阴道分泌物检查结果示正常率为98.36%高于B组为91.80%(P<0.05),其总有效率为96.72%高于B组为88.52%(P<0.05),临床各症状缓解率高于B组(P<0.05)。结论:HPV所致宫颈糜烂患者给予干扰素-α2a栓与微波抗病毒治疗,能显著地改善患者的临床症状,促进阴道分泌物清洁的疗效较为确切。
Objective: To evaluate the clinical efficacy of interferon-α2a suppository in the treatment of patients with cervical erosion with human papillomavirus (HPV) infection. Methods: 122 patients with cervical erosion caused by HPV were selected from February 2014 to October 2016. They were randomly divided into group A and group B, with 61 cases in each group. Patients in group B received microwave treatment and patients in group A On the basis of group B plus interferon-α2a suppository antiviral therapy, the two groups of patients before and after treatment to assess the cleanliness of vaginal discharge, the total effective rate and clinical symptom relief. Results: The results of vaginal discharge examination in the two groups showed no significant difference (P> 0.05). After treatment, the vaginal secretions in group A showed a normal rate of 98.36% (P <0.05). The total effective rate was 96.72% higher than that in group B (88.52%) (P <0.05). The clinical symptom relief rate was higher than that in group B (P <0.05). Conclusion: Interferon-α2a suppository and microwave anti-virus therapy can effectively improve the clinical symptoms and promote the vaginal discharge of patients with cervical erosion caused by HPV more accurately.