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成人注用瑞芬太尼(remifentanil)的消除半衰期为3～10min,因为它与甲酯基连续所以被血液和组织中非特异性酯酶所降解。作者在门诊试用瑞芬太尼给小儿进行斜视矫正手术,并与阿芬太尼、异氟醚或异丙酚作比较,共选择2～12岁(ASAⅠ～Ⅱ级)患儿123例。术前用咪唑安定,吸氟烷-氧化亚氮-氧气,静注维库溴铵和阿托品,行气管插管,吸70％N_2O-30％O_2,维持
The elimination half-life of remifentanil in adults is 3 to 10 minutes, which is degraded by non-specific esterases in blood and tissues because it is continuous with the carbomethoxy group. The trial of remifentanil in outpatients for strabismus surgery in children and compared with alfentanil, isoflurane or propofol, a total of 123 children aged 2 to 12 years (ASA Ⅰ ~ Ⅱ grade) were selected. Premedication with midazolam, sevoflurane - nitrous oxide - oxygen, intravenous vecuronium and atropine, tracheal intubation, suction 70% N_2O-30% O_2, to maintain