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作者指出利福平与异烟肼均被作为治疗结核病的基础药物,至今利福平仅有口服制剂,然而有些结核病人因病情危重或一般情况差,需经胃肠外给药。本文报导了使用利福平静脉给药病人的临床资料,并着重评价病人对此治疗的耐受性,和血液中的药物浓度。总计19例(男15,女4),年龄1~87岁(其中2例小孩系结核性脑膜炎患者)。临床诊断肺结核病10例,结核性脑膜炎4例,其他播散性结核病4
The authors note that both rifampicin and isoniazid are used as the basic drugs for the treatment of tuberculosis. Since rifampicin has only been given as an oral preparation, some TB patients need parenteral administration because of their critically ill or poor general condition. This article reports the clinical data of patients on the use of rifampicin and highlights the patient’s tolerance to this treatment and the concentration of the drug in the blood. A total of 19 patients (15 males and 4 females) aged 1 to 87 years (2 of whom were tuberculous meningitis). Clinical diagnosis of tuberculosis in 10 cases, 4 cases of tuberculous meningitis, other disseminated tuberculosis 4