The aim of the following essay is to find a semantic core pattern, characterizing its ontology or metaphysics, in the form of thinking that emerged in the work of Descartes, spread and was modified through Spinoza and Leibniz, and became the panorama of science-oriented philosophies constituting the implicit or explicit underpinnings of contemporary thinking, research, and debate, especially in relation to the study of meaning and mind. The aim of the following essay is to find a semantic core pattern, characterizing its ontology or metaphysics, in the form of thinking that emerged in the work of Descartes, spread and was modified through Spinoza and Leibniz, and became the panorama of science-oriented philosophies make the implicit or explicit underpinnings of contemporary thinking, research, and debate, especially in relation to the study of meaning and mind.