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目的:分析二维超声斑点追踪成像(2D-STI)及三维斑点追踪成像(RT-3DE)对甲状腺功能亢进患者左心室纵向收缩功能及同步性评价的价值。方法:选择2018年7月至2019年8月在诸暨市第二人民医院初次确诊为甲状腺功能亢进(甲亢)的患者93例为甲亢组,同时选择同期在该院体检中心进行健康体检的健康志愿者93例为对照组,均行2D-STI和RT-3DE检查,获得两组左心室纵向收缩功能参数及同步性参数,并对比其差异。结果:两组常规超声检查左心房内径(LAD)、左心室收缩末期内径(LVEDS)、左心室舒张末期内径(LVEDD)及室间隔厚度(IVST)及左心室射血分数(LVEF)等参数差异均无统计学意义(均n P>0.05);2D-STI示甲亢组患者左心室多个节段纵向收缩峰值均显著较对照组提前[后壁基底段:(15.27±3.21)%比(20.38±4.19)%,n t=9.336,n P<0.001;侧壁基底段:(16.54±4.68)%比(21.26±5.65)%,n t=6.204,n P<0.001;前间隔基底段:(12.84±5.26)%比(18.43±6.06)%,n t=6.718,n P<0.001;后壁中间段:(16.44±5.13)%比(22.75±6.06)%,n t=7.664,n P<0.001;前间隔中间段:(12.03±4.41)%比(19.25±5.16)%,n t=10.257,n P<0.001;下壁心尖段:(14.36±5.06)%比(21.46±6.28)%,n t=8.489,n P<0.001;心尖帽:(9.43±5.28)%比(12.35±6.43)%,n t=3.384,n P<0.001];甲亢组2D-STI同步性参数Tls-16-SD较对照组显著延长[(82.45±15.25)%比(52.45±10.65)%,n t=15.553,n P<0.001]。RT-3DE示甲亢组患者左心室多个节段纵向收缩峰值均显著低于对照组[前壁基底段:(11.48±5.33)%比(19.17±6.49)%,n t=8.830,n P<0.001;侧壁基底段:(15.62±3.77)%比(22.08±4.56)%,n t=10.529,n P<0.001;下壁中间段:(15.65±3.37)%比(18.39±4.25)%,n t=4.871,n P<0.001;后间隔中间段:(14.39±5.36)%比(19.62±3.38)%,n t=7.959,n P<0.001;前壁心尖段:(11.17±5.54)%比(18.29±6.24)%,n t=8.228,n P<0.001;室间隔心尖段:(14.67±5.38)%比(20.53±4.34)%,n t=8.175,n P<0.001];甲亢组RT-3DE同步性参数Tmsv-16-SD较对照组显著延长[(84.36±16.08)%比(55.27±11.17)%,n t=14.328,n P0.05).2D-STI showed that the longitudinal systolic peak of multiple segments of left ventricle in the hyperthyroidism group was significantly earlier than that in the control group[posterior basal segment: (15.27±3.21)% vs.(20.38±4.19)%,n t=9.336, n P<0.001; lateral basal segment: (16.54±4.68)% vs.(21.26±5.65)%,n t=6.204, n P<0.001; anterior septal basal segment: (12.84±5.26)% vs.(18.43±6.06)%,n t=6.718, n P<0.001; posterior middle segment: (16.44±5.13)% vs.(22.75±6.06)%,n t=7.664, n P<0.001; middle anterior septum: (12.03±4.41)% vs.(19.25±5.16)%,n t=10.257, n P<0.001; apical inferior wall: (14.36±5.06)% vs.(21.46±6.28)%,n t=8.489, n P<0.001; apical cap: (9.43±5.28)% vs.(12.35±6.43)%,n t=3.384, n P<0.001]. Compared with the control group, the 2D-STI synchronization parameter Tls-16-SD of the hyperthyroidism group was significantly longer[(82.45±15.25)%, (52.45±10.65)%,n t=15.553, n P<0.001]. RT-3DE showed that the peak longitudinal contraction of multiple segments of left ventricle in hyperthyroidism group was significantly lower than that in the control group[front wall basal segment: (11.48±5.33)% vs.(19.17±6.49)%,n t=8.830, n P<0.001; side wall basal segment: (15.62±3.77)% vs.(22.08±4.56)%,n t=10.529, n P<0.001; the middle section of the bottom wall: (15.65±3.37)% vs.(18.39±4.25)%,n t=4.871, n P<0.001; the middle section of the posterior interval: (14.39±5.36)% vs.(19.62±3.38)%,n t=7.959, n P<0.001; the apex of the front wall segment: (11.17±5.54)% vs.(18.29±6.24)%,n t=8.228, n P<0.001; apical segment of ventricular septum: (14.67±5.38)% vs.(20.53±4.34)%,n t=8.175, n P<0.001]. RT-3DE synchronization parameter Tmsv-16-SD in the hyperthyroidism group was significantly longer than that in the control group[(84.36±16.08)%, (55.27±11.17)%,n t=14.328, n P<0.001].n Conclusion:2D-STI and RT-3DE can objectively evaluate left ventricular longitudinal systolic function and synchrony in patients with early hyperthyroidism.