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口腔鳞状细胞癌(oral squamous cell carcinoma,OSCC)是最常见的口腔恶性肿瘤,它的发生与细胞周期调控机制的紊乱所导致细胞的失控性生长密切相关。细胞周期的运行受多种因素所调控。有两个主要调控点:一个处于G1/S转折点,是控制细胞进入S期的控制点(G1期检测点),另一个处于G2/
Oral squamous cell carcinoma (OSCC) is the most common oral malignant tumor, and its occurrence is closely related to the uncontrolled growth of cells caused by the disorder of cell cycle regulation. The cell cycle is regulated by many factors. There are two main control points: one at the G1 / S turning point, a control point that controls the cell’s entry into the S phase (G1 test point) and the other at the G2 /