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[目的] 观察10%鸦胆子乳联合地塞米松保留灌肠治疗溃疡性结肠炎的临床疗效。[方法] 10%鸦胆子乳50 ml加地塞米松5 mg混合充分摇匀,用18~20号肛管每晚经肛门插入保留灌肠 2 h,1 个月为 1 个疗程。如未治愈可进行第2个疗程治疗。疗程结束后均经结肠镜复查。[结果] 48 例患者经 1 个疗程治愈 38 例(78.5%),其中轻度32例,中度6例;好转10例(21.5%),其中中度6例,重度4例。伴腺瘤息肉2例,炎性息肉5例。1例腺瘤息肉经2个疗程灌肠治疗,腺瘤脱落,另1例腺瘤息肉者行肛肠科手术;5 例炎性息肉经治疗均消失。其余病例均获临床治愈,其治愈率为97.5%。[结论] 该疗效理想而可靠,简便易行,值得临床尝试和推广。
[Objective] To observe the clinical effect of 10% brucea combined with dexamethasone retention enema in the treatment of ulcerative colitis. [Method] 10% Brucea javanica 50 ml plus dexamethasone 5 mg mixed well, with 18 to 20 anal peritoneal enema retention enema 2 h, 1 month for a course of treatment. If not cured can be the first two courses of treatment. Colonoscopy after the end of treatment review. [Result] 48 cases were cured by one course of treatment (38 cases, 78.5%), of which 32 cases were mild and 6 were moderate; 10 cases were improved (21.5%), 6 cases were moderate and 4 cases were severe. Accompanied adenoma polyps in 2 cases, 5 cases of inflammatory polyps. One case of polyp of adenoma was treated by two courses of enema, the adenoma was shed, and the other one was treated by anorectal surgery with polyp of adenoma. Inflammatory polyp disappeared in 5 cases. The remaining cases were clinically cured, the cure rate was 97.5%. [Conclusion] The curative effect is ideal and reliable, easy to operate and worthy of clinical trial and promotion.