目的 :进一步探讨末端病中潮线“涨潮”现象的发生机制及意义。方法 :采用 1 3只Wistar雄性大鼠 ,随机分为空白对照组 5只、造模组 8只 (用电击跳跃法造模 4周 ) ,取其跟腱末端进行HE染色 ,重点观察潮线变化 ,并进行力学分析。结果 :对照组末端潮线为位于纤维软骨区与钙化软骨区之间的蓝染的平滑的分界线 ,其弧度与跟骨轮廓基本一致 ;但造模组的“涨潮”现象明显 :潮线呈现不规则的“火焰”样的蓝线 ,有的部位成为封闭的小圆圈 ,其弧度向纤维软骨区的方向推进 ,几乎与跟腱纤维垂直。结果表明 ,潮线“涨潮”是由于跟腱末端区承受负荷 ,纤维软骨区不同步的钙化造成的。这是人体对负荷应力的适应性变化 ,有加大跟腱作用力臂 ,使跟腱各部分纤维均匀受力的作用 Objective: To further explore the mechanism and significance of “high tide” in the tide line of terminal disease. Methods: Thirteen Wistar male rats were randomly divided into blank control group (n = 5) and model group (n = 8) (model of electroshock jump method) for 4 weeks. HE staining was performed on the ends of Achilles tendon to observe the change of tide line , And mechanical analysis. Results: The tidal line at the end of the control group was the smooth boundary of blue dye between the fibrocartilaginous area and the calcified cartilage area, and its radian was basically consistent with the contour of the calcaneus. However, the phenomenon of “high tide” in the model group was obvious: the tide line appeared Irregular “flame” like blue line, and some parts of the closed small circle, the curvature of the fiber cartilage area to promote the direction, almost perpendicular to the Achilles tendon fibers. The results show that the tide line “high tide” is caused by the calcification of the end-zone of the Achilles tendon that is not synchronized with the cartilage area. This is the human body adaptability to changes in stress, there is an increase of Achilles tendon arm, so that all parts of the Achilles tendon fiber force