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目的研究血浆D-二聚体(D-dimer)与纤维蛋白原(FIB)的动态变化对早期预测盆腔手术后下肢深静脉血栓(DVT)的意义,探讨彩色多普勒超声检查对患者DVT的早期诊断价值。方法选取2014年1月至2016年1月在首都医科大学附属北京潞河医院妇科择期行盆腔手术并具有DVT高危因素的231例患者为研究对象,术前所有患者下肢深静脉彩色多普勒超声检查均为阴性。根据患者术后72~120 h下肢彩色多普勒超声检查结果,将患者分为血栓组(n=36)和非血栓组(n=195)。所有患者于手术前、术后第1天和术后第3天晨检测D-dimer和FIB,并进行统计分析。结果血栓组与非血栓组比较,术后D-dimer和FIB显著增高,差异有统计学意义(P<0.05),与术前比较,两组患者术后D-dimer和FIB显著增高,差异有统计学意义(P<0.05)。结论血浆D-dimer、FIB检测结合彩色多普勒超声检查对妇科盆腔术后患者并发下肢DVT的早期诊断具有重要价值。
Objective To study the dynamic changes of plasma D-dimer and fibrinogen (FIB) in early prediction of lower extremity deep vein thrombosis after pelvic surgery (DVT), to explore the color Doppler ultrasonography in patients with DVT Early diagnosis. Methods From January 2014 to January 2016, 231 patients who underwent pelvic surgery undergoing pelvic surgery with high risk of DVT at Beijing Luhe Hospital affiliated to Capital Medical University from January 2014 to January 2016 were enrolled in this study. All patients underwent deep venous color Doppler ultrasonography All tests were negative. Patients were divided into thrombus group (n = 36) and non-thrombus group (n = 195) according to the results of color Doppler ultrasonography of lower limbs at 72 ~ 120 h after operation. D-dimer and FIB were detected in all patients before surgery, on the first day after surgery and on the third day after surgery, and statistical analysis was performed. Results Compared with non-thrombus group, D-dimer and FIB increased significantly after operation (P <0.05). Compared with preoperative, the D-dimer and FIB were significantly increased in both groups Statistical significance (P <0.05). Conclusion Plasma D-dimer and FIB combined with color Doppler ultrasonography is of great value in the early diagnosis of pelvic postoperative pelvic complications in lower extremities.