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目的:探讨痰热清对急性胰腺炎(AP)合并急性肺损伤(ALI)患者的治疗作用。方法:79例AP病例,53例采取常规治疗,26例加用痰热清治疗,观察ALL／急性呼吸窘迫综合征的发生率,并记录血气指标和外周血IL-6,IL-8及TNF-α水平。结果:常规治疗组和痰热清治疗组ALI发生率分别为56．6％和30．8％(P<0．05);痰热清治疗组之PaO2和PaO2／FiO2高于非痰热清治疗组;患者外周血TNF-α、IL-6和IL-8在痰热清治疗后显著下降(P<0．05)。结论:痰热清能有效降低AP患者急性肺损伤的发生率,改善ALI/ARDS时的低氧血症状态。
Objective: To investigate the therapeutic effect of Tanreqing on acute pancreatitis (AP) combined with acute lung injury (ALI). Methods: 79 cases of AP, 53 cases were treated with routine treatment, 26 cases were treated with Tanreqing and the incidence of ALL/ARDDS was observed. Blood gas indexes and peripheral blood IL-6, IL-8 and TNF were recorded. -α level. Results: The incidence of ALI was 56.6% and 30.8% in the conventional treatment group and Tanreqing treatment group, respectively (P<0.05). PaO2 and PaO2/FiO2 were higher in the Tanreqing treatment group than in the non-detergent fever group. In the treatment group, the levels of TNF-α, IL-6, and IL-8 in the peripheral blood were significantly decreased after treatment with Tanreqing (P<0.05). Conclusion: Qinreqing can effectively reduce the incidence of acute lung injury in AP patients and improve the state of hypoxemia in ALI/ARDS.