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目的:探讨宫颈液基细胞学检查(TCT)与组织病理学诊断的符合情况,评估宫颈TCT在妇科普查宫颈疾病中的价值;分析不同民族妇女之间宫颈疾病的发病率,以指导宫颈疾病的防治工作。方法:对5 681例新疆伊犁地区不同民族、不同年龄妇女作宫颈TCT,结果异常者依次作宫颈多点活检病理学检查。细胞学诊断采用TBS(the bethesda system)2001分级报告系统,性质未定的不典型鳞状细胞(ASCUS)及以上病变诊断为阳性,所有ASCUS以上病变的患者行病理组织学诊断,对两者进行统计学分析。结果:5 681例患者中ASCUS 369例,低度鳞状上皮内瘤变(LSIL)77例,高度鳞状上皮内瘤变(HSIL)29例。筛查发现宫颈浸润癌(CA)7例。汉族和维吾尔族妇女宫颈癌前病变宫颈上皮内瘤变(CIN)和CA的发病率略高于其他民族,但差异无统计学意义(P>0.05)。结论:各民族妇女定期进行宫颈TCT可及早发现宫颈的早期病变,从而减少各民族,尤其是汉族和维吾尔族妇女宫颈癌的发生率,同时改善宫颈癌的诊治结果。
OBJECTIVE: To investigate the coincidence of cervical cytology (TCT) and histopathological diagnosis, to evaluate the value of cervical TCT in gynecological census of cervical diseases, and to analyze the incidence of cervical diseases among different ethnic women in order to guide the cervical disease Prevention and control work. Methods: Cervical TCT was performed in 5 681 women of different nationalities and ages in Yili Prefecture of Xinjiang. Results of abnormalities were sequentially examined by multiple biopsy of cervix. Cytological diagnosis using TBS (the bethesda system) 2001 grading system, the nature of undetermined atypical squamous cells (ASCUS) and the above lesions were diagnosed as positive, all ASCUS lesions in patients with histopathological diagnosis, the two statistics Analysis. Results: There were 369 cases of ASCUS in 5 681 cases, 77 cases of low grade squamous intraepithelial neoplasia (LSIL) and 29 cases of high grade squamous intraepithelial neoplasia (HSIL). Screening found that cervical cancer (CA) in 7 cases. The incidence of cervical intraepithelial neoplasia (CIN) and CA in Han and Uighur women with cervical precancerous lesions was slightly higher than that in other ethnic groups, but the difference was not statistically significant (P> 0.05). Conclusion: Regular cervical TCT among ethnic women can detect early cervical lesions and reduce the incidence of cervical cancer among ethnic groups, especially Han and Uighur women, and improve the diagnosis and treatment of cervical cancer.