腹膜粘连仍是腹部手术后常见的并发症。腹膜内纤维性粘连可以引起严重的机械性肠梗阻、女性不育及慢性盆腔痛。其原因包括手术损伤、炎症反应、异物残留、组织缺血等。目前预防纤维性粘连的方法有抗炎症反应、应用抗生素、物理和化学性屏障。但临床上尚无广泛应用的好方法。对粘连形成的病理生理学过程进行细胞和分子机制的探讨,可以为预防粘连提出更有效的方法。 Peritoneal adhesions are still common complications after abdominal surgery. Intraperitoneal fibrosis can cause serious mechanical obstruction, female infertility and chronic pelvic pain. The reasons include surgical injury, inflammation, foreign body residues, tissue ischemia. The current methods of preventing fibrotic adhesions have anti-inflammatory responses, the use of antibiotics, physical and chemical barriers. But there is no clinical application of a good method. The discussion of the cellular and molecular mechanisms of the pathophysiology of adhesion formation can provide a more effective method for preventing adhesion.