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目的探讨肺炎支原体感染可诱发咳嗽变异性哮喘。方法对36例合并肺炎支原体感染的慢性咳嗽患儿进行回顾性分析。结果给予大环内酯类抗生素及美普清治疗。18例患儿咳嗽于7d内消失,15例2周内消失,3例4周内消失。结论肺炎支原体感染可能诱导咳嗽变异性哮喘的发生,尤其是有特异性体质及家族史者。因此对慢性咳嗽的患儿应考虑到肺炎支原体感染的可能性,对确诊为肺炎支原体感染并应用大环内酯类治疗后疗效欠佳者要考虑到咳嗽变异性哮喘的可能性,伍用支气管扩张剂。
Objective To investigate whether Mycoplasma pneumoniae infection can induce cough variant asthma. Methods Thirty-six children with chronic cough with mycoplasma pneumoniae infection were retrospectively analyzed. The results given macrolide antibiotics and meprazole treatment. 18 cases of children cough disappeared within 7d, 15 cases disappeared within 2 weeks, 3 cases disappeared within 4 weeks. Conclusions Mycoplasma pneumoniae infection may induce the development of cough variant asthma, especially those with specific constitution and family history. Therefore, children with chronic cough should take into account the possibility of Mycoplasma pneumoniae infection, diagnosis of Mycoplasma pneumoniae infection and application of macrolide treatment ineffective to take into account the possibility of cough variant asthma, Wu Bronchial Expansion agent.