目的探讨进食对Fibroscan检测肝脏受控衰减参数(CAP值)及其诊断脂肪肝的影响。方法使用Fibroscan测量10例志愿者【7名健康人和3名经B超诊断的脂肪肝患者,平均年龄29岁(21~39)岁;体质指数为(19.83~29.70)kg/m~2,平均为(22.7±3.13)kg/m~2)】空腹(CAP0)、进食后30 min(CAP30)、120 min(CAP120)和次日空腹(CAP02)肝脏CAP值的差异,并比较空腹与进食后CAP值诊断脂肪肝的准确性。结果受检者CAP0、CAP30、CAP120和CAP02分别为(227.8±59.5)d B/m、(244.9±42.1)d B/m、(241.1±51.4)d B/m和(245.7±49.4)d B/m,差异无统计学意义(H=0.62,P=0.89);空腹(空腹和次日空腹)与餐后(餐后30 min和120 min)CAP值差值比较,差异也无统计学意义(Z=-1.37,P=0.17),但空腹与餐后检测诊断脂肪肝的误诊率分别为5%和15%(x~2=0.28,P=0.59)。结论进食对Fibroscan检测CAP值的结果影响不显著,但或可增加诊断脂肪肝的误诊率。 Objective To investigate the effect of feeding on Fibroscan in detecting the controlled attenuation parameter (CAP) of liver and diagnosis of fatty liver. Methods Fibroscan was used to measure 10 volunteers [7 healthy individuals and 3 fatty liver patients diagnosed by B ultrasound, mean age 29 years (21-39) years old; body mass index (19.83-29.70) kg / m ~ 2, The mean CAP was (22.7 ± 3.13) kg / m ~ 2). The differences of CAP in the fasting (CAP0), 30 min (CAP30), 120 min (CAP120) and the second fasting (CAP02) After the CAP value diagnosis of fatty liver accuracy. Results The CAP0, CAP30, CAP120 and CAP02 were (227.8 ± 59.5) d B / m, (244.9 ± 42.1) d B / m, (241.1 ± 51.4) d B / m and (245.7 ± 49.4) d B / m, the difference was not statistically significant (H = 0.62, P = 0.89); there was no significant difference in CAP value between fasting (fasting and next day fasting) and postprandial (30 min and 120 min after meal) (Z = -1.37, P = 0.17). However, the misdiagnosis rates of fasting and postprandial diagnosis of fatty liver were 5% and 15% respectively (x2 = 0.28, P = 0.59). Conclusion The results of Fibroscan in detecting CAP value are not significant, but may increase the misdiagnosis rate of fatty liver diagnosis.