患者女,42岁。既往无胃痛、反酸病史。为预防心脑血管疾病于每晚睡前口服肠溶阿司匹林80mg,连服3个月后大便呈黑色并感乏力、食欲减退1周,但患者未予注意,继续服用该药2天,突然腹痛,3小时后恶心、呕吐咖啡样物、腹泻黑色稀便2次,急诊入院。查大便潜血阳性,紧急胃镜检查:胃粘膜普遍充血水肿、弥漫性点状出血、部分胃粘膜糜烂。于胃镜下孟氏液局部喷射止血,用甲氰咪呱0.2g×3支加入5％葡萄糖注射液250ml Female patient, 42 years old. No previous history of stomach pain and acid reflux. In order to prevent cardiovascular and cerebrovascular diseases, oral enteric-coated aspirin 80mg was taken orally every night before going to bed at night. Even with 3 months after taking the stool, the stool was black and weak and the appetite was reduced for 1 week. However, the patient did not notice and continued to take the medicine for 2 days. Sudden abdominal pain , 3 hours after nausea, vomit coffee samples, diarrhea black loose stool twice, emergency admission. Check stool occult blood positive, emergency gastroscopy: General congestion and edema of the gastric mucosa, diffuse punctate bleeding, partial gastric mucosal erosion. In the gastroscope Monteggia local injection to stop bleeding, with cimetidine 0.2g × 3 5% glucose injection by adding 250ml