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目的 应用动脉导管超选择性技术治疗晚期及复发性盆腔恶性肿瘤 6 7例。方法 应用Seldinger法一侧股动脉插管 ,将导管超选至双侧髂内动脉的肿瘤直接供血动脉 ,经导管灌注抗癌药物后 ,应用碘油 (与大剂量顺铂混合 )及明胶海绵栓塞。结果 完全有效 2 5 .4%、部分有效 71.6 %、轻微有效 3 .0 %。半年、1年、2年生存率分别为 :10 0 %、74.6 %、5 5 .2 %。无严重合并症病例发生。结论 我们认为经导管超选择髂内动脉灌注大剂量顺铂化疗与碘油、明胶海绵栓塞联合应用治疗晚期及复发性盆腔恶性肿瘤是安全有效的。
Objective To use the arterial catheter superselective technique to treat 67 cases of advanced and recurrent pelvic malignant tumors. Methods Seldinger method was used to intubate one side of the femoral artery. The catheter was directly selected into the bilateral internal iliac arteries and the tumor was directly delivered to the blood artery. After infusion of anticancer drugs through the catheter, lipiodol (mixed with large dose of cisplatin) and gelatin sponge embolization was used. . The results were fully valid 25.4%, partially effective 71.6 %, and slightly effective 3.0 %. The half-year, 1-year, and 2-year survival rates were: 10%, 74.6%, and 55.2%. No serious complications occurred. Conclusions We believe that transcatheter arterial infusion of high-dose cisplatin chemotherapy combined with lipiodol and gelatin sponge embolization is safe and effective in the treatment of advanced and recurrent pelvic malignancies.