目的:探讨利用医院信息系统数据的集成构建涵盖广泛的用于药物上市后再评价的大型数据库系统的可行性和必要性,为中药上市后再评价HIS(hospital information system)集成数据仓库的构建提供总体设计思路和方法。方法:通过对国内外利用电子信息系统开展基于真实世界的临床试验设计的分析和对比,结合我国医院信息系统的特性,从设计思路、设计特点、存在问题和解决办法等几个方面对总体构架进行设计和探讨。结果:提出了中药上市后再评价HIS集成数据仓库的设计方案,指明了建设的途径和方法。结论:提出的中药上市后再评价HIS集成数据仓库的设计方案具有高内聚低耦合、安全、通用、高效、可维护性好的特点,可以有效解决多家医院HIS数据集成过程中的问题和挑战,具有实用价值。 OBJECTIVE: To explore the feasibility and necessity of constructing a large-scale database system for re-evaluation after drug listing by using the integration of hospital information system data to provide the re-evaluation of the establishment of hospital information system (HIS) integrated data warehouse Overall design ideas and methods. Methods: Based on the analysis and comparison of clinical trial design based on real world using electronic information system at home and abroad, combined with the characteristics of hospital information system in our country, this paper analyzed the overall framework from several aspects of design ideas, design features, problems and solutions Design and explore. Results: The design scheme of reusing HIS integrated data warehouse after the listing of TCM was put forward, and the ways and methods of construction were pointed out. Conclusion: The proposed re-evaluation of HIS integrated data warehouse after the listing of traditional Chinese medicine has the characteristics of high cohesion, low coupling, safety, generality, high efficiency and good maintainability. It can effectively solve the problem of HIS data integration in many hospitals and Challenge, with practical value.