目前 ,儿童难治性肾病的治疗仍是临床上较为棘手的问题 ,由于其病因、发病机制、病理类型不同而直接影响其疗效及预后。近年来有关大剂量环磷酰胺静脉冲击疗法 (ＣＴＸ ＰＴ)治疗小儿难治性肾病的报道较多 ,但结果不尽相同。我们的研究显示 ,ＣＴＸ ＰＴ治疗小儿难治性肾病综合 At present, the treatment of children with refractory nephropathy is still a more clinically difficult problem, due to its etiology, pathogenesis, different pathological types directly affect the efficacy and prognosis. In recent years, high-dose cyclophosphamide venous pulse therapy (CTX PT) treatment of children with refractory renal disease reported more, but the results are not the same. Our study shows that CTX PT treatment of refractory nephrotic syndrome in children