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［目的］探讨轮叶党参多糖的抗肿瘤作用．［方法］按标准方法给 ５０只小鼠接种Ｓ１８０肉瘤细胞 后，随机分成 ４组：①对照组：每天灌胃蒸馏水 １０ ｍＬ／ｋｇ；②实验 １组：每天灌胃轮叶党参多糖 ０．５ ｇ／ｋｇ； ③实验 ２组：每天灌胃轮叶党参多糖 １ｇ／ｋｇ；④实验 ３组：每天灌胃轮叶党参多糖 ２ ｇ／ｋｇ．连续 １０ｄ后，观 察瘤重及体重．［结果］０．５，１．０，２．０ ｇ／ｋｇ的轮叶党参多糖对 Ｓ１８０。肉瘤生长抑制率分别为 １５％，３５％及 ５４％，中剂量和高剂量的抑制率高于对照组．高剂量组的体重下降幅度低于对照组．［结论］轮叶党参多 糖对小鼠Ｓ１８０肉瘤有抑制作用．
[Objective] To study the anti-tumor effect of Codonopsis Pilosula polysaccharide. [Methods] 50 mice were inoculated with S180 sarcoma cells according to the standard method and were randomly divided into 4 groups: 1 control group: distilled water 10 mL/kg per day; 2 group 1: daily administration of Codonopsis lanceolata polysaccharide 0.5 g/kg; 3 experiment 2 groups: daily gavage of Codonopsis pilosula polysaccharide 1g/kg; 4 experiment 3 groups: daily gavage codonopsis lanceolata polysaccharide 2 g/kg. After 10 days in succession, the tumor weight and body weight were observed. [Results] 0.5, 1.0, 2.0 g/kg of Codonopsis pilosula polysaccharide on S180. The inhibition rate of sarcoma growth was 15%, 35% and 54%, respectively. The inhibition rates of medium and high doses were higher than those of the control group. The weight loss of the high-dose group was lower than that of the control group. [Conclusion] Codonopsis pilosula polysaccharide inhibited S180 sarcoma in mice.