目的讨论7.5%高渗氯化钠溶液+聚明胶肽在高海拔地区创性休克中的疗效及作用机制。方法将36例休克患者先用7.5%高渗氯化钠溶液(5ml/kg体重),而后输入聚明胶肽500ml,再输入平衡盐。结果(5~10)分钟起作用,血压明显回升,平均维持(40~60)分钟。结论高渗盐+聚明胶能迅速有效地改善血容量休克病人重要脏器的血流灌注,血压迅速回升,尤其在高原缺氧环境下对创伤性休克复苏更具有重要的临床意义。 Objective To discuss the effect and mechanism of 7.5% hypertonic sodium chloride solution + polygeline in high-altitude invasive shock. Methods Thirty-six patients with shock were treated with 7.5% hypertonic sodium chloride solution (5ml / kg body weight) and then 500ml of poly Results (5 ~ 10) minutes of work, blood pressure rose significantly, the average maintained (40 ~ 60) minutes. Conclusion Hypertonic saline + poly gelatin can rapidly and effectively improve the perfusion of vital organs in patients with hemorrhagic shock and the blood pressure rises rapidly, especially in traumatic shock and resuscitation under altitude hypoxia.