北京地区汉族健康人HLA-A,B,C位点抗原频率及基因频率的分布

来源 :北京医科大学学报 | 被引量 : 0次 | 上传用户:misscxj890417L
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本文应用Bodmer萤光染色微量淋巴细胞毒法测定北京地区汉族健康人HLA-A,B,C位点抗原及基因频率。发现在北京地区汉族人中,HLA-B21并不罕见,主要为Bw 50亚型。并且首次检出国内尚未报告的B21新亚型,它的反应格局是只和HLA-B21和B6抗血清反应,而不和B49及Bw50亚型血清反应。 In this paper, HLA-A, B and C antigenicity and gene frequencies of healthy Han people in Beijing were determined by Bodmer fluorescent microdialysis of lymphocytes. It was found that HLA-B21 was not uncommon among Han Chinese in Beijing, mainly Bw 50 subtypes. And for the first time detected a new subtype B21 in China that has not been reported yet. Its response pattern is only reacted with HLA-B21 and B6 antisera, but not with B49 and Bw50 subtype sera.
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