目的了解大学新生血尿酸(BUA)水平和高尿酸血症(HUA)检出率及其与体质量指数(BMI)的相关性,为早期预防控制提供依据。方法对5 269名大学新生入学健康体检检测血尿酸及身高、体重,分析血尿酸水平和高尿酸血症检出率,并对血尿酸正常组和高尿酸血症组的体质量指数进行比较。结果 5 269名大学生的高尿酸血症总患病率为15.43%,其中男生患病率为28.30%,女生患病率为1.72%,男生高于女生(P<0.01);男生平均血尿酸值为(400.4±85.9)μmol/L,显著高于女生的(285.8±55.2)μmol/L(P<0.01)。HUA组新生超重/肥胖的检出率明显高于BUA正常组(χ2=353.92,P<0.01)。结论大学生血尿酸水平和高尿酸血症与性别、体质量指数密切相关。应早期干预大学生高尿酸血症的预防,倡导健康的生活方式。 Objective To investigate the relationship between freshmen’s blood urea nitrogen (BUA) level, hyperuricemia (HUA) detection rate and body mass index (BMI), so as to provide basis for early prevention and control. Methods A total of 5 269 college freshmen were enrolled in the study. Blood uric acid, body weight, serum uric acid level and hyperuricemia were detected. The body mass index of normal uric acid group and hyperuricemia group were compared. Results The prevalence of hyperuricemia in 5 269 college students was 15.43%. The prevalence of boys was 28.30%, the prevalence of girls was 1.72%, the boys were higher than girls (P <0.01) (400.4 ± 85.9) μmol / L, which was significantly higher than that of girls (285.8 ± 55.2) μmol / L (P <0.01). The prevalence of overweight / obesity in HUA group was significantly higher than that in normal BUA group (χ2 = 353.92, P <0.01). Conclusion The level of serum uric acid and hyperuricemia in college students are closely related to gender and body mass index. Should be early intervention in the prevention of college students with hyperuricemia, advocate a healthy lifestyle.