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目的通过1例经克拉屈滨治疗的复发毛细胞白血病的病例分析,进一步了解毛细胞白血病的治疗策略和方法。方法观察2012年4月我院收治的1例经克拉屈滨治疗的毛细胞白血病复发患者的治疗过程,分析毛细胞白血病的临床特点、治疗方法、治疗效果及不良反应,并复习有关文献。结果此例患者经1个疗程克拉屈滨治疗,3个月后达到部分缓解,随访5个月持续部分缓解。结论克拉屈滨是治疗毛细胞白血病的有效方法,不良反应小,耐受性好,适合在中国毛细胞白血病患者中应用。
Objective To further understand the treatment strategies and methods of hairy cell leukemia by analyzing a case of recurrent hairy cell leukemia treated with cladribine. Methods The clinical course of hair cell leukemia patients treated with cladribine treated in April 2012 in our hospital was analyzed. The clinical features, treatment, treatment and adverse reactions of hairy cell leukemia were analyzed. The related literatures were reviewed. Results The patient was treated with one course of cladribine. After 3 months, partial remission was achieved, and partial remission was maintained for 5 months. Conclusions Cladribine is an effective treatment for hairy cell leukemia with small adverse reactions and good tolerability, which is suitable for the application in Chinese hair cell leukemia patients.