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β2微球蛋白(β2-MG)与多种疾病有关,它虽不是肿瘤特异性标志物,但却是有价值的辅助诊断指标。综合文献资料提示,膀胱癌患者多有血、尿β2-MG增高,尿/血β2-MG比值升高,膀胱癌术后β2-MG浓度下降;如术后监测β2-MG明显升高者,多为病情恶化,预后不好,而其值低者则预后较好,生存较长;膀胱癌细胞表面β2-MG表达与肿瘤分级、分期及疗效判断及预后密切相关。
β2 microglobulin (β2-MG) and a variety of diseases, although it is not a tumor-specific markers, but it is a valuable diagnostic indicator. The comprehensive literature suggests that more bladder cancer patients with blood, urinary β2-MG increased urinary / serum β2-MG ratio, β2-MG decreased after bladder cancer surgery; such as postoperative monitoring of β2-MG was significantly higher, Prolonged disease progression and poor prognosis, whereas patients with lower values had better prognosis and longer survival time. The expression of β2-MG on the surface of bladder cancer cells was closely related to tumor grade, staging, curative effect and prognosis.