左旋门冬酰胺酶(L-Asparaginase,L-Asp)是治疗儿童急性淋巴细胞白血病(Acute LymphoblasticLeukemia,ALL)的重要药物。十余年来,在提高患儿生存率方面起了重要作用。L-Asp已成为我科ALL病人诱导缓解和强化治疗的必用药,在广泛的临床应用过程中,L-Asp存在一定的不良反应。本文总 L-asparaginase (L-Asparaginase, L-Asp) is an important drug for the treatment of childhood acute lymphoblastic leukemia (ALL). More than ten years, has played an important role in improving the survival rate of children. L-Asp has become a necessary drug for inducing remission and intensive treatment in ALL patients in our department. L-Asp has some adverse reactions in a wide range of clinical applications. This article always