患者男,63岁。全身红斑伴瘙痒、反复发热4个月。外院多次以“多形红斑”、“湿疹”予甲泼尼龙片、沙利度胺口服,病情好转,停药后半月皮疹突发全身,瘙痒剧烈。查体:全身散在约花生大小椭圆形暗红斑,境界欠清,对称分布;双侧腋下、腹股沟、颈部、锁骨上、右侧颌下浅表淋巴结肿大,四肢末梢袜套样痛觉减退,双侧病理征(+)。骨髓穿刺活检提示骨髓增生极度活跃,骨髓瘤细胞占63.5%,瘤细胞大小不等,形态异常,可见体积大、双核、多核胞浆丰富的瘤细胞。诊断:多发性骨髓瘤。转至中医科化疗。 Male patient, 63 years old. Whole body erythema with itching, repeated fever for 4 months. Outside the hospital many times to “polymorphic erythema ”, “eczema ” to methylprednisolone tablets, thalidomide oral, improved condition, half a month after stopping the rash burst body, severe itching. Physical examination: the body scattered about the size of the oval-shaped peanut-shaped erythema, the state less clear, symmetrical distribution; bilateral armpits, groin, neck, supraclavicular, right submandibular superficial lymph nodes, distal limb sock-like pain relief, Bilateral pathological sign (+). Bone marrow biopsy showed hypermyotrophic bone marrow hyperplasia, myeloma cells accounted for 63.5%, tumor cells ranging in size, abnormal morphology, we can see bulky, dual-nuclear, multi-nuclear cytoplasm rich tumor cells. Diagnosis: Multiple myeloma. Go to Chinese medicine chemotherapy.